Webdithiolethiones compounds, particularly (4-phenyl-1,2-dithiole-3-thione), exhibit the biological activity against Staphylococcus aureus. Antibacterial activity showed value ranged from 1.02 to 1.428 mg/ml (MIC). All of the tested dithiolethiones and antibiotics were inactive against Escherichia coli and Pseudomonas aeruginosa, except WebDec 1, 2008 · Dithiolethiones are a well-known class of cancer chemopreventive agents; the key mechanism of action of dithiolethiones involves activation of Nrf2 signaling and induction of phase II enzymes.

Dithiolethiones: a privileged pharmacophore for anticancer …

Webdithiolethione (plural dithiolethiones) ( organic chemistry ) Any (especially cyclic) dithiole derivative of a thione Retrieved from " … WebOct 19, 2016 · Dithiolethiones, a class of sulfur-containing heterocyclic molecules, are known to increase cellular levels of glutathione; however, limited information is available … the definite article in french

Evaluation in-vitro the antioxidant activity of some dithiolethiones

WebJan 1, 2010 · Dethionation of dithiolethiones to 1,2-dithiole-3-ones was accomplished by mercury(ii)-promoted hydrolysis. A preliminary investigation of the dithiolethiones and dithiole-3-ones as inhibitors of ... WebThe invention relates to dithiolethiones derivatives as monoamino oxidase inhibitors, in particular MAO-B inhibitors, to methods for the preparation of these compounds and to novel intermediates useful for the synthesis of said dithiolethiones derivatives. The invention also relates to the use of a compound disclosed herein for the manufacture ... WebBackground: Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system characterized by demyelination of neurons and neurodegeneration. Current MS therapies ameliorate inflammatory damage but are unable to address the degenerative aspects of the disease. Objective: In this report, we evaluate the ability of amide-based … the definite integral for n 0 is called the