Chromomycin-a3

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August undefined, 2024

WebApplication: Chromomycin A3 is a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye CAS Number: 7059-24-7 Purity: ≥97% Molecular Weight: 1183.25 Molecular Formula: C 57 H 82 … WebChromomycin A3 from Streptomyces griseus C57H82O26 CID 15953908 - structure, chemical names, physical and chemical properties, classification, patents, literature ...

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WebG-C specific intercalating agents [actinomycin D (AMD) and chromomycin A3 at 1 microM] also prevented ER disappearance; ethidium bromide (EB) and quinacrine were ineffective. AMD and CHX operated immediately after their addition to the medium indicating an inhibitory action on the synthesis of an RNA and/or a peptide with high turnover rate ... WebChromomycin A3 from Streptomyces griseus is an antibiotic exhibiting anti-bacterial, anti-fungal and antitumor activities. [ 3] It serves as a fluorescent DNA stain. [ 4] It is useful for the detection of protamine deficiency in sperm chromatin. inclusive vs parallel gateway

R显带 - 维基百科，自由的百科全书

Web其显示的人类染色体带型与Q带或G带相反，异染色质区如染色体的，一般在Q带或G显带中深染，常染色质区浅染，而R带则异染色质区一般浅染，常染色质区深染。. 其他R显带的方法包括用chromomycin A3或olivomycin等荧光素染色，或在细胞周期的合成期（S期）将 ... WebDescription. Chromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced … WebChromomycin A 3 is an anthraquinone antibiotic and antitumor agent isolated from S. griseus that is used as a fluorescent probe for DNA with excitation/emission spectra of 445/575 nm. 1, 2 Its DNA binding is specific to two or more contiguous GC base pairs, which makes it suitable for characterizing heterochromatin in plants with species ... inclusive wage system

Chromomycin A3 (CAS 7059-24-7) - Cayman Chem

WebChromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced DNA binding of … WebChromomycin A3 has a variety of utilities as a staining agent for human sperm chromatin, autophagy inducing agent, and apoptosis inhibitor. For research use only. We do not sell to patients. Chromomycin A3 … inclusive vs exclusive statisticsWebJun 7, 2024 · The Chromomycin A3 (CMA3) and Acridine orange (AO) staining were performed to examine the sperm DNA fragmentation status. CCl4 treatment showed a significant decrease in antioxidant markers and sperm count, viability, normal morphology and motility as well as significantly increased the testicular oxidative stress markers, and … inclusive washroom

"WebChromomycin A3 from Streptomyces griseus is an antibiotic exhibiting anti-bacterial, anti-fungal and antitumor activities. [ 3] It serves as a fluorescent DNA stain. [ 4] It is useful … " - Chromomycin-a3

Chromomycin-a3

Sperm DNA Fragmentation and Male Infertility - Academia.edu

WebChromomycin A3 is an antibiotic that binds to the GC-rich sequence of DNA in the presence of divalent cations, inhibiting DNA replication and transcription (1). It is also used as a … WebChromomycin A3 (CMA3) Protamination state of the spermatozoa determines its chromatin integrity status. The lesser the protamine content, the poorer the DNA packaging and the higher the sperm DNA damage. CMA3 binds to the sperm DNA deficient of protamine and stains light yellow [74]. The intensity of color is high in sperm with increased prot ...

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WebIn-Person Course Schedule - Industrial Refrigeration …. 1 week ago Web Ends: Apr 21st 2024 5:00PM. Fee: $1,225.00. Register By: Apr 17th 2024 2:17PM. Collapse. This is a … Chromomycin A3 (CMA3) or Toyomycin is an anthraquinone antibiotic glycoside produced by the fermentation of a certain strain of Streptomyces griseus (No. 7). See more In the presence of Mg ions, Chromomycin A3 binds reversibly to DNA, preferentially to contiguous G/C base pairs. When bound to DNA, Chromomycin A3 has a maximum excitation wavelength of 445 See more • in-vitro membrane-impermeant G/C-specific fluorescent DNA-binding dye. • in-vitro antibiotic of gram-positive bacteria, through inhibition of the incorporation of Pi in the RNA. • in-vitro anticancer drug that inhibits RNA synthesis. See more

WebChromomycin A₃ - CAS 7059-24-7 - Calbiochem Antitumor antibiotic that inhibits RNA synthesis. A cell-permeable fluorescent dye that can be used with Bisbenzimide H 33258 … WebChromomycin A3 as a fluorescent probe for flow cytometry of human gynecologic samples Author R H Jensen PMID: 70448 DOI: 10.1177/25.7.70448 Abstract Chemical, physical and optical properties of chromomycin A3 are examined so as to ascertain appropriate staining and analysis procedures for flow cytometry of human gynecologic samples.

WebThe biosynthetic gene cluster of the aureolic acid type antitumor drug chromomycin A3 from S. griseus subsp. griseus has been identified and characterized. It spans 43 kb and … WebJan 29, 2024 · CMA3 is an anthraquinone glycosidic antibiotic, produced by Streptomyces griseus ( 21 ). The anti-cancer effects of CMA3 have been proposed since the 1960s ( 22, 23 ). Side effects of CMA3 in advanced breast cancers have interrupted that use ( 24) but it is widely used for DNA staining ( 25 ).

WebJan 14, 2024 · Description. Chromomycin A3 is an aureolic acid-type antitumor antibiotic. Chromomycin A3 forms dimeric complexes with divalent cations, such as Mg2+, which strongly binds to the GC rich sequence of DNA to inhibit DNA replication and transcription. Chromomycin A3 has a variety of utilities as a staining agent for human sperm …

WebChromomycin a3 C57H82O26 CID 656673 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. inclusive vs relative fitnessWebChromomycin A3 and mithramycin are antibiotics binding preferentially to the GC-rich regions of DNA. They have excitation maxima at 440 nm and emission maxima at 555 and 575 nm, respectively. Unfortunately the low fluorescence intensity … inclusive wan essential pintsWebChromomycin A3. 230752-10MG. 80055-168EA 310.68 USD. 80055-168. Chromomycin A3. Chromomycin A3. Antibiotic that inhibits RNA synthesis. Excitation maximum: … inclusive waste recycling consortiumWebNov 19, 1985 · The binding of chromomycin A3 to calf thymus DNA and poly (dG-dC) has been studied by 13C and 1H NMR with emphasis on the mode of binding, the role of Mg2+, and pH effects. inclusive washroom signageWeb丁香通为您找到694条(+)-打碗花精 a3厂家的工商注册年份、员工人数、年营业额、信用记录、主营产品、相关(+)-打碗花精 a3产品的供求信息、交易记录等企业详情。丁香通为买家提供用户服务，诚信保障等服务，批发采购(+)-打碗花精 a3，上丁香通。 inclusive walt disney world package dealWebApr 6, 2024 · Chromomycin A3 (CMA3, Figure 17.1) is an antibiotic glycoside produced by the fermentation of a certain strain of Streptomyces griseous. In the presence of bivalent … inclusive washroom signsWebChromomycin A3 450 570 B, BV G-C Range 4, 6-Diamidino-2-Phenylindole HCl (DAPI) 372 456 U A-T Range Ethidium Bromide 545 605 G, IG DNA•RNA Hoechst 33258 365 465 U A-T Range Hoechst 33342 355 465 U A-T Range Mithramycin 395 570 BV G-C Range Olivomycin 430 ... inclusive water parks holiday in egypt